Taking LEXIVA

Convenience with LEXIVA

Fewer pills

LEXIVA is often taken with another HIV medicine called ritonavir. Ritonavir increases or "boosts" the effect of LEXIVA by making it last longer in the body.

A recent medical study has shown that LEXIVA can be taken with half the dose of the ritonavir than before—100 mg (1 pill) versus 200 mg (2 pills). Half the amount of ritonavir means fewer pills to take and keep track of every day and more convenience.

Take it once-a-day

If your healthcare provider recommends it, you might be able to take LEXIVA with ritonavir just once a day. Plus, LEXIVA does not have to be taken with food. You can eat and drink whenever you like when taking LEXIVA.

You can take LEXIVA with ritonavir once a day in the following ways:

LEXIVA (two 700 mg tablets) plus ritonavir (one 100 mg tablet)
LEXIVA (two 700 mg tablets) plus ritonavir (two 100 mg tablets)

Once-daily LEXIVA with ritonavir is recommended only for people who have not taken protease inhibitors before. If you have taken protease inhibitors before, LEXIVA can also be taken twice a day. Ask your healthcare provider if LEXIVA is right for you.

Next: Learn more about how LEXIVA works.

See the full Prescribing Information for LEXIVA

LEXIVA^® (fosamprenavir calcium)

Indication and Usage:

LEXIVA treats HIV infection in adults. It should always be used in combination with other HIV medicines. These medicines do not cure HIV infection/AIDS or prevent passing HIV to others.

Important Safety Information

You should not take LEXIVA if you have had an allergic reaction to LEXIVA or AGENERASE^® (amprenavir)
High blood sugar, diabetes or worsening of diabetes, and bleeding in hemophiliacs have occurred in some patients taking protease inhibitors
When you start taking HIV medicines, your immune system may get stronger and could begin to fight infections that have been hidden in your body, such as pneumonia, herpes virus, or tuberculosis. If you have new symptoms after starting your HIV medicines, be sure to tell your doctor
Changes in body fat may occur in some patients taking antiretroviral therapy. The cause and long-term health effects of these conditions are not known at this time
Skin rashes can occur in patients taking LEXIVA. Rarely, rashes were severe or life threatening
Opportunistic infections can develop when you have HIV and your immune system is weak. It is very important that you see your healthcare provider regularly while you are taking LEXIVA to discuss any side effects or concerns
Most common side effects in clinical studies were diarrhea, headache, nausea, rash, and vomiting. In most cases, these side effects did not cause people to stop taking their medicine

DRUG INTERACTIONS

LEXIVA should not be taken with: AGENERASE^® (amprenavir), Halcion^® (triazolam), ergot medications (Cafergot^®, Migranal^®, D.H.E. 45^®, and others), Propulsid^® (cisapride), Versed^® (midazolam), Orap^® (pimozide), Zocor^® (simvastatin), Mevacor^® (lovastatin), Rifadin^® (rifampin), Rescriptor^® (delavirdine mesylate), or St. John's wort (Hypericum perforatum). If you are taking Norvir^® (ritonavir), you should not take Tambocor^® (flecainide), or Rythmol^® (propafenone hydrochloride)
Serious and/or life-threatening events could occur between LEXIVA and other medications, including Cordarone^® (amiodarone), lidocaine (intravenous only), Elavil^® (amitriptyline HCl) and Tofranil^® (imipramine pamoate), tricyclic antidepressants, and Quinaglute^® (quinidine)
Women who use birth control should choose a different kind of contraception. LEXIVA can affect the safety and effectiveness of birth control pills.
Patients taking Viagra^® (sildenafil citrate) or LEVITRA^® (vardenafil HCl) with LEXIVA may be at an increased risk of side effects
This list of drug interactions is not complete. Be sure to tell your healthcare provider about all medicines you are taking or plan to take, including over-the-counter drugs, vitamins, and herbals